BRCA2-deficient cells precipitate telomere shortening upon collapse of stalled replication forks. Here, we report that the dynamic interaction between BRCA2 and telomeric G-quadruplex (G4), the non-canonical four-stranded secondary structure, underlies telomere replication homeostasis.

The patterning of poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) hydrogels with excellent electrical property and spatial resolution is a challenge for bioelectronic applications.

Recent multi-omics analyses paved the way for a comprehensive understanding of pathological processes. However, only few studies have explored Alzheimer’s disease (AD) despite the possibility of biological subtypes within these patients. For this study, unsupervised classification of four datasets (genetics, miRNA transcriptomics, proteomics, and blood-based biomarkers) using Multi-Omics Factor Analysis+ (MOFA+),

A substantial part of China’s anthropogenic emissions has been offset by its land carbon sink, which represents an important element in achieving carbon neutrality by 2060.

Thermogenic adipocytes generate heat to maintain body temperature against hypothermia in response to cold. Although tight regulation of thermogenesis is required to prevent energy sources depletion, the molecular details that tune thermogenesis are not thoroughly understood.

Many statistical methods for pathway analysis have been used to identify pathways associated with the disease along with biological factors such as genes and proteins.

Professor Tae-Young Yoon's team from the School of Biological Sciences announced that they have revealed the folding mechanism of glucose transporter, a complex membrane protein, for the first time using magnetic tweezers.

Professor Tae-Woo Lee's team in the Department of Material Engineering announced that they have developed the world's most effective large-scale light-emitting diodes by using metal halide perovskites, which is a promising material for lighting devices.

The joint research team led by Professor Sunghoon Kwon from the Department of Electrical and Computer Engineering and Professor Wonshik Han from the College of Medicine announced that they have developed a platform for discovering targets for new chemotherapy drugs by using technology used for analyzing cancer RNA editome.

The joint research team led by Professor Buhm Han from the Department of Biomedical Sciences and Professor Keehoon Jung from the Department of Anatomy and Cell Biology announced that they have succeeded in developing a new AI algorithm for analyzing single-cell RNA-seq data.

The research team led by Professor Yang-Ki Cho from the School of Earth and Environmental Sciences announced that they have scientifically proved that rapid ocean current changes and rise in sea surface temperature occurred during the period when the number walleye pollocks dramatically decreased.

The research team led by Professor Jae Bum Kim from the School of Biological Sciences revealed that the accretion of senescent obese adipocytes causes inflammation in fat tissues and insulin resistance which can lead to metabolic diseases.